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De Angelis ML, Francescangeli F,Aric E,Verachi P,Zucchetti M, Matteo C, Petricci E,Pilozzi E,Orienti I,Boe A

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Gradient ethanol precipitation further exploits the inverse correlation between polysaccharide molecular weight and ethanol precipitation concentration: higher molecular weight fractions precipitate at lower ethanol concentrations, enabling molecular weight-based fractionation

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However, low solubility and low targeting during drug delivery remain an insurmountable gap in DFO therapy

Ferulic acid supplementation for six weeks at a dose of 1000 mg daily in a randomized, double-blind, placebo-controlled clinical trial resulted in significant reductions in total cholesterol, Low-Density Lipoprotein Cholesterol (LDL-C), triglycerides, and oxidative stress marker levels, followed by an increase in High-Density Lipoprotein Cholesterol (HDL-C)