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These products have poor bioavailability due to their low permeability ( In rat plasma following intragastrical administration of 100 mg/kg ASD, M4, and M5 were detected with a comparable AUC level of M0, while M1, M2, and M3 concentrations were trace (data not shown)

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Studies frequently explore cellular signaling, actin and cytoskeletal organization, angiogenic markers, and stress-response pathways