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Further optimization of the timing, dose, and duration of IGF-1R mAb treatment is warranted in order to maximize benefits while minimizing risks, particularly given recent evidence that transient administration of other drugs can have persistent benefits on age-related outcomes 43

Importantly, this study also demonstrated that the B12 reduction associated with metformin use is not transitory but persists and progresses over time and, in some patients, to levels at which replacement is recommended

The right answer depends on what stalled and what your bloodwork shows

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GLP-1 Agonists: Reducing Appetite and Controlling Blood Sugar GLP-1 (glucagon-like peptide-1) agonists are a popular class of peptides for weight loss