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Many providers set a minimum weight, commonly around 100 pounds, in addition to an age minimum, because fluid and nutrient dosing is calculated based on body mass

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We used our model to test the importance of glucoronidation and its sensitivity to the activity of the glucoronosyl tranferase enzymes by computing the amount of liver damage resulting from a moderate overdose (10 g) with different choices for the V max values of the glucoronosyl tranferases

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Intgr Med (Encinitas)