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Conventional delivery of antioxidants faces several challenges, including poor bioavailability, low stability, rapid clearance, short half-life, poor targeting, non-specific distribution, gastrointestinal degradation, low penetration of biological barriers, cytotoxicity, and pro-oxidant effects at high doses [31]

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7, 2010, pp

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Employing positive ion electrospray LC-MS/MS with precursor ion scanning and product ion scanning, two novel electrophilic metabolites, kawain 11,12-quinone and 7,8-dihydrokawain 11,12-quinone were identified in their glutathione conjugate form (Figure 5)

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Resistance of -crystallin quaternary structure to UV irradiation

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Dihydrolipoamide dehydrogenase (DLD) regenerates the oxidized form using NAD+ as an electron acceptor, completing the catalytic cycle [37]

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doi: 10.1515/jpem-2019-0245

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