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In addition, it has been recently shown that dietary fructose enhances tumor growth indirectly via interorgan lipid transfer, specifically lysophosphatidylcholines 51

For instance, repeated light-dark cycles reduced NK cell cytotoxicity and increased lung tumor burden in rats, while alternating light-dark cycles durations impaired both delayed-type hypersensitivity (DTH) responses and phagocytosis 88,89

Note the need for TCA recycling of GABA within astrocytes

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Timmusk T, Palm K, Metsis M, Reintam T, Paalme V, Saarma M, et al

Testicular atrophy and hypothalamic pathology in COVID-19: Possibility of the incidence of Male infertility and HPG axis abnormalities