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Description
While polyol pathway activation and accumulation of fructose and sorbitol are implicated in hyperglycemic-induced damage, the precise metabolites that govern pericyte dysfunction and survival remain largely unknown
This includes cell shrinkage, chromatin condensation, and membrane blebbing
In highly oxidizing environment the role of GSH as a reducing agent is significant
Progress tends to slow after that, which is normal, phentermine is a jump-start, not a long-term solution
Pandit A, Bhave S
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