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doi: 10.1016/j.jaci.2009.03.007
This is felt to be due to the detoxification effect of B12 in patients who have methylation issues
Therefore, the surveillance of SAM by mitochondria at the site of bioenergetics and biosynthesis might have been effective for microorganisms in the metric of evolutionary fitness
If the activity of methylmalonyl-CoA mutase is absent or decreased, e.g., due to hereditary defects of the apoprotein or to B 12 deficiency, toxic methylmalonic acid (MMA) is formed and the excess of methylmalonic acid is excreted in the urine
Dark Comedy 01:47:51 Drugs, Overdose, Comedian Deaths, Mental Health
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