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The pathogenesis of MTX-induced renal impairment is thought to be mediated by either MTX and its metabolites precipitating in the renal tubules or MTXs direct toxic impact on the renal tubules (Reference Widemann and Adamson6)
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Voeding die rijk is aan carnitine zijn voornamelijk dierlijke producten zoals vlees (lam, rund, varken), kabeljauw, kaas en melk

The TF-VIIa complex enhances platelet sensitivity to agonists such as adenosine diphosphate (ADP), thrombin, and collagen

Hannaian SJ, Churchward-Venne TA
Rustin P, Chretien D, Bourgeron T, Grard B, Rtig A, Saudubray JM, Munnich A (1994) Biochemical and molecular investigations in respiratory chain deficiencies
