glutathione peroxidase and thioredoxin Exploring the System as a Therapeutic Target in Cancer: Mechanisms Implications Frontiers | The Role of
Description
In vitro and in vivo studies have shown that genetic and pharmacological inhibition of USP14 induces degradation of an androgen receptor (AR), favoring tumor suppression in AR-positive breast cancer cells or prostate cancer cells (Liao et al., 2017

Idriss et al., 2018

PMID 5641006

injection, 750 mg/kg/day) 25,50 to the mice (Fig
00154-X/asset/114b9911-e5dd-439c-bc10-9dad7b72ab06/main.assets/gr3.jpg)
doi: 10.1016/j.cbi.2007.02.008

The skin, joints, blood vessels and internal organs are variably affected (Table 1)
