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For every 1 gram daily of carnitine supplementation, up to 4 grams, the results showed a significant mean reduction in the following compared with controls: BMI: 0.37 kg/m3 Fasting plasma glucose: 3 mg/dL HbA1c: 0.16% LDL cholesterol: 4 mg/dL Total cholesterol: 5 mg/dL Triglycerides: 6 mg/dL The greatest reductions in BMI were observed at 2 grams daily whereas serum triglycerides, total cholesterol, and fasting plasma glucose had the greatest improvements at 4 grams daily (Mirrafiei 2024)

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Muscles have high levels of carnitine

PPAR- ligands, such as Wy-14,643, were reported to have an antifibrotic action in the rat thioacetamide (TAA) model of liver cirrhosis [14]

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According to the study: Excessive amounts of omega-6 polyunsaturated fatty acids (PUFA) and a very high omega-6/omega-3 ratio, as is found in todays Western diets, promote the pathogenesis of many diseases, including cardiovascular disease, cancer, and inflammatory and autoimmune diseases, whereas increased levels of omega-3 PUFA (a low omega-6/omega-3 ratio) exert suppressive effects