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2.3 Diagnosis and management Peripheral fatigue can be quantified through objective assessments of strength and aerobic capacity, while central fatigue is evaluated using self-reports and validated questionnaires that capture the patients perception of physical and mental exertion impacts on their activities and exertion levels

Further research is needed to explore p53-targeted therapies that inhibit p53 aggregation

J Affect Disord 16:2731 [DOI] [PubMed] [Google Scholar] 26.Crook H, Raza S, Nowell J, Young M, Edison P (2021) Long covid-mechanisms, risk factors, and management

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