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Hyperinsulinemia and its pivotal role in aging, obesity, type 2 diabetes, cardiovascular disease and cancer

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Voss, M

Delaying ferroptosis-targeted therapies until late symptomatic stages severely limits their potential efficacy [128]

Although delivering neurotrophic factors via genetically modified MSCs shows promise for neuroprotection in neurodegenerative diseases, poor post-transplant survival and host immune response, such as microglial activation and astrocyte recruitment, remain significant barriers to clinical translation