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Importantly, AOD-9604 does not bind to growth hormone receptors or stimulate IGF-1 production, which distinguishes it from full-length human growth hormone

[27] Additionally, anyone with Lebers hereditary optic neuropathy (a rare inherited eye disease) must avoid cyanocobalamin injections, since B can precipitate rapid worsening of that condition
Related NNMT-inhibitor programs are at the preclinical or early discovery stage in industry

This chart may be useful as an overview: What Are The Symptoms of Vitamin B12 Deficiency

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