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From these studies, it is unclear whether, ultimately, it is the accumulation of oxidized phospholipids that is essential for the nuclear transmigration of AIF or whether hydrogen peroxide stimulates apoptogen release by other mechanisms

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b , Gross appearance of E12.5 embryos of the indicated genotypes

all three trials demonstrated reduced adverse effects of the chemotherapy without negative effects on the effectiveness of the regimen, suggesting some physiologic effect from oral dosing

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