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Likewise, radiation leads to persistent oxidative stress that has implications with early and late effects of radiation (Datta et al., 2012)

Apoptosis in ischemic renal injury: roles of GTP depletion and p53

Asahara T, Murohara T, Sullivan A, Silver M, Van Der Zee R, Li T, et al

The reduction of ZIP14 in obese patients negatively correlated with both leptinemia and adipose tissue leptin levels in obesity, as in ZIP14 knockout mice, which exhibited higher levels of leptin

Thus, it potentially induces genotoxicity and apoptosis in human peripheral blood lymphocytes (116)