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In each condition, 200 ng of the 5XUAS-tk-luc reporter was transfected, together with 25 ng of the pCMV-Gal4- Dmrta2 or pCMV-Gal4 and different doses of pCDNA3-Myc- Zfp423 (200, 400, and 600 ng) expression plasmids

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The participants took cognitive tests and underwent tests to determine their arterial stiffness a well-established cardiovascular risk factor for cognitive impairment and closely linked with high blood pressure

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These mechanisms would be the plausible explanation for the cause of 1,2-DCP-related cholangiocarcinoma, especially in extrahepatic cases that are proposed to arise from the biliary epithelium and peribiliary gland 43