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In men, total sperm count, progressive motility, and sperm DNA fragmentation index all improved in a number of animal studies and small human reports
In response to stressful conditions, it trimerizes, translocates into the nucleus, binds to the heat shock element of target genes and activates the transcription of HSPs, including HSP70/90 (Noble and Shen, 2012)
But for some researchers, this novel side effect may influence the risk-benefit calculation when choosing between the two compounds
