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Our goal has been to do enough proof-of-principle that people will accept that stapled peptides can get into cells and act on important targets

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The first generation of anti-tau antibodies, most of which targeted the proteins polymerization-driving N terminus, failed in clinical trials
Thymosin 4 induces angiogenesis in critical limb ischemia mice via regulating Notch/NFB pathway

Chen W-H, Xu X-D, Luo G-F, Jia H-Z, Lei Q, Cheng S-X, et al

Elevated NNMT activity has been associated with increased fat accumulation, reduced metabolic efficiency, and impaired cellular energy production
