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CYP46A1 knockdown in the mouse striatum induced a decrease of 24 S-OHC levels and produced a spontaneous striatal neurodegeneration associated to abnormal balance and motor coordination
Osburn et al., 2006
Food Chem Toxicol, 47: 220229

NAD+ & cellular metabolism Explored in cell research on how NNMT inhibition affects NAD+ and SAM levels investigational, animal and in-vitro only
In odor learning, pairing with an aversive stimulus has no negative effect until postnatal day 1012 (Haroutunian and Campbell, 2010)
