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3.6.3 Mechanisms of association between UPF intake and ADHD Increasing evidence suggests that UPF consumption may contribute to ADHD risk and symptom expression through multiple biological pathways, including lipid metabolism, epigenetic programming, exposure to neurotoxins, and dopaminergic dysfunction (Table 2)

Higher inflammatory state is believed to be involved in the development and maintenance of hypertension [3], but many of the mechanisms that start and then maintain this elevated inflammatory state are yet to be determined

Infiltration of the thyroid gland associated with a spectrum of disease processes, such as sarcoidosis, hemochromatosis, hematologic malignancies, solid malignancies, and infectious agents, can impair functioning to a sufficient degree to cause hypothyroidism

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Systematic identification of cyclic-di-GMP binding proteins in Vibrio cholerae reveals a novel class of cyclic-di-GMP-binding ATPases associated with type II secretion systems