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Asymmetric Enzymatic Synthesis of Allylic Amines: A Sigmatropic Rearrangement Strategy

For example, in Sickle Cell Anemia and Thalassemia the altered Hbs are less stable resulting in increased intracellular oxidative reactions that damage the cell membrane and increase RBC lysis (Nagababu et al., 2001a)

Johns National Academy of Health Sciences, Bangalore, India Vivek Bhat Global Health Division, Global Health Research and Medical Interventions for Development, Kathmandu, Nepal Suraj Bhattarai Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, UK Suraj Bhattarai Department of Anatomy, Royal College of Surgeons in Ireland Medical University of Bahrain, Busaiteen, Bahrain Vijayalakshmi S

S., Kamendulis, L

The membrane transporter P-glycoprotein (P-gp) is encoded by ABCB1 and is an ATP-dependent drug efflux pump

G., Bollen, P