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Description
Given the potential of reduced gliotoxin to thiolate cellular proteins, we speculate that reduced gliotoxin may be sequestered into intracellular vesicles where it is converted to the oxidized form, by an unidentified activity, prior to release from the cell by an exocytotic mechanism complementary to GliA-mediated efflux (Figure 7)
The British journal of nutrition

Neuron 102, 435449.e6

The ability to predict compound concentrations and exposure durations that could cause a significant compromise in cellular antioxidant defence as a function of a physicochemical property, especially with respect to an understated mechanism such as redox cycling, could prove to be extremely useful when investigating toxicity with the reduction of animal models in mind

Author contributions WL: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing original draft

Information theory links those two quantities
