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- Melone, M.A.B

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Therefore, targeting mitochondrial mechanisms makes sense
It can pass easily to the brain and is both water and fat-soluble Liu and colleagues tested aged rats with oral acetyl-L-carnitine and lipoic acid to see if the supplementation reduced mitochondrial aging in the brain [1] A group from Oregon State University reviewed the literature and suggested that together, acetyl-L-carnitine and lipoic acid were able to protect the heart from aging as well as reverse age-related changes [2]
Comprehensive review of the expanding roles of the carnitine pool in metabolic physiology: beyond fatty acid oxidation

1991;5 Suppl 1:97-105
