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Increased intestinal permeability facilitates the translocation of microbes, their components, and microbial products into the blood stream and their recognition by the host immune cells (Longo et al., 2020)
Vitamin B12, in particular, is known for its role in energy metabolism
Downstream, the compound modulates serotonin handling along the brain-gut axis, an area Vukojevic and colleagues have reviewed in central-nervous-system applications
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