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PMID: 19 SeoG-YTakahashiDWangQMikulskiZChenAChouT-Fet al

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This connection is particularly significant given that antibody titers after vaccination decline more rapidly in the elderly [389], highlighting the potential role of zinc in supporting more robust and sustained immune responses in aging populations

Furthermore, the kidneybrain axis reflects the role of renal impairment in exacerbating neuroinflammation, metabolic imbalance, and toxin accumulation relevant to PD pathology