glutathione cleavable linker Tandem-cleavage linkers require two sequential enzymatic steps to A Review on ADC Linkers:

Based on their nature and their effects, this heterogeneous group of drugs has been divided into four subgroups: classical nootropic compounds, substances increasing brain metabolism, cholinergic, and plants and their extracts with nootropic effects

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Excessive copper levels in the liver have been demonstrated to result in a number of physiological consequences, including mitochondrial dysfunction, the downregulation of copper influx, the upregulation of metallothioneins (MTs), and ultimately, cell death

G protein-coupled estrogen receptor 1 negatively regulates the proliferation of mouse-derived neural stem/progenitor cells via extracellular signal-regulated kinase pathway

This property has been attributed to its gastric juice protein origin