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Abbreviations GSH: Glutathione PAL: Phenylalanine ammonia-lyase CAD: Cinnamyl alcohol dehydrogenase POD: Peroxidase PG: PGSC0003DMG40 SA: Salicylic acid IAA: Indole-3-acetic acid (auxin) JA: Jasmonic acid qRT-PCR: Quantitative real-time polymerase chain reaction References Liu R, Zhang ZH, Chen SJ, Wang ZH

d , LX-2 cells were transfected with APOL2 WT or APOL2 2A for 6 h and subsequently treated with or without DP (1 M) for 48 h

5a, b), whereas OPA1 and TOMM20 protein turnover remained unaltered (Fig

Although only IL-1-induced cyclo-oxygenase 2 (COX2) production and IL-8 secretion could be attenuated by the ERK1/2-specific inhibitor PD98059, both TNF- and IL-1 activate ERK and induce the expression of IL-8 and IL-6 [128]

During this process, PLA particles were colonized by gut microbes, forming surface biofilms and increasing pullulanase activityan enzyme that degrades branched polysaccharidesthe authors suggested this may have broken down PLA into smaller carbon-rich molecules, potentially supporting Bifidobacterium growth, without triggering pathogenic overgrowth or inflammatory responses (Jimnez-Arroyo et al., 2023)