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(2021) 53:e13644
Does not contain dyes, preservatives or sweeteners

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While it does not cure PEM, it may help raise the threshold at which a crash is triggered, providing patients with a slightly larger, more forgiving energy envelope

Pain is also intensified during a rebound from a painkiller, such as an opioid medication, a phenomenon known as opioid-induced hyperalgesia
The same may be performed later in life as late-onset symptoms appear
