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Insulin-like growth factor-1, as discussed earlier, has implications on lipid and glucose metabolism [87, 88], and its exogenous administration enhances insulin sensitivity in healthy adults [139, 140] as well as those with T2D [155]

Vitamin B12 deficiency symptoms Weakness, tiredness, or lightheadedness Heart palpitations and shortness of breath Pale skin A painful, smooth, inflamed tongue (glossitis) Digestive issues Bluish or gray-brown nails Loss of appetite What happens if your vitamin B12 deficiency is left untreated

Most of the time these "side effects" are not a true B12 side effect

Groenewegen, A., Rutten, F

Key physiological effects include: Stimulates lipolysis the breakdown of stored triglycerides into free fatty acids
