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While NAC indirectly boosts glutathione synthesis, L-Glutathione participates in critical cellular processes, including protein folding, DNA synthesis, and apoptosis regulation through thiol-disulfide exchange reactions

It is unclear if the effects of NAC on oxidative stress are due to these antioxidant properties or due to increased glutathione synthesis

doi: 10.3390/ijms20030609

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This rapid GSH loss disrupts redox homeostasis, promotes ROS accumulation, and facilitates redox-dependent protein modifications that drive apoptotic commitment

Relying solely on food sources may limit the potential for significant increases in glutathione levels
