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Canonical and non-canonical Hedgehog signalling and the control of metabolism

True HHS develops slowly and should be corrected slowly

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Similarly, curcumin modulates lipid metabolism in THP-1-derived macrophages by upregulating lipid transport genes such as CD36/FAT and FABP-4, leading to lipid accumulation and potentially limiting lipid utilization by tumor cells, ultimately inhibiting tumor growth (135, 136)

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Oxidative stress levels are raised in chronic fatigue syndrome and are associated with clinical symptoms