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doi: 10.1016/j.ijcard.2013.12.014

Conclusions The compounds that are able to reduce toxic effects exerted by BaP act through various mechanisms: Decrease of AhR translocation (e.g., resveratrol, curcumin) Downregulation of Cyp 450 level and other proteins involved in BaP metabolism (e.g., resveratrol, curcumin) Decrease of BPDA-DNA adducts and other DNA damage formation (e.g., curcumin
Vredenburg et al., 2014

Subjective improvements such as increased energy, enhanced mental clarity, or noticeable changes in skin quality can indicate that your therapy is effective

Its principal contribution lies in reframing WD as a disorder of systemic mitochondrial vulnerability to copper toxicity and in opening new avenues for mechanistically informed therapeutic development

Relative peak intensity values were normalized to 10 6 cells per sample
