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Therapeutic potential of organosulfur compounds in pulmonary hypertension

[PubMed Citation] Pregnant animal studies Reproductive and developmental toxicity studies performed in rats at oral doses up to 6.7 times the recommended human intravenous dose and in rabbits at doses up to 3.3 times the recommended human intravenous dose revealed no evidence of impaired fertility or embryofetal toxicity

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Neurochem Int 145:105008

In addition, drug absorption from the DG muscle may be slower than other sites and this can lead to a build-up of drugs in the tissues and risk of overdose (Malkin, 2008)

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