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doi: 10.3389/fncel.2025.1584767
The details below come from AP reporting and public FDA records
PMID 12735695
Prodrug-based nanoparticulate drug delivery strategies for cancer therapy
10.1007/s12035-016-9924-0 66
AKR1B1 also participates in steroid hormones catabolism and plays an important role in the regulation of steroid function in several tissues (Barski et al., Nevertheless, AKR1B1 also has a negative side since it can promote tumor chemoresistance and contribute to the perpetuation of inflammation and to the development of secondary diabetic complications (Figure 2)
