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In 2021, Dr

Environ Monit Assess

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Various preclinical models have been created that are showing the impact of metabolism on brain function and in particular the role that impaired metabolism plays in the neurodegeneration processes

Interestingly, embryonic THC exposure selectively decreases CB1 in the hippocampus of male mice at postnatal day 20 in parallel to decreased CB1-expressing GABA interneurons, resulting in impaired spatial memory in male adult mice (de Salas-Quiroga et al., 2020)

[DOI] [PMC free article] [PubMed] [Google Scholar] 75.Dikalova A.E., Pandey A., Xiao L., Arslanbaeva L., Sidorova T., Lopez M.G., Billings F.T., Verdin E., Auwerx J., Harrison D.G., et al