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In these settings, LDL particles may be cholesterol-depleted but numerous, causing LDL-C to underestimate risk

Critically, acute AMPK activation during ATP depletion exacerbates glycolytic overdrive and FAO, while chronic mTORC1 signaling in surviving neurons drives maladaptive lipid synthesis that fuels ferroptosis [111]

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Concentration of total protein was spectrophotometrically determined using commercial diagnostic kits supplied by Diamond (Egypt) according to the method of Bowers and Wong [28]