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Neurology 80 , 8591 (2013)
10.1371/journal.pone.0051912 PLoS One 230 TanakaA.ClelandM
This memory effect is linked to epigenetic mechanisms that allow the genome to regulate its function while retaining genetic information
-arrestin2 thus functions as a critical adaptor for recruiting the E3 ubiquitin ligase NEDD4 that ubiquitinates agonist-activated 2 ARs [68, 81]

However, its appearance can be cosmetically unsatisfactory and many women seek to reduce it
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