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While PD is primarily associated with motor symptoms due to the degeneration of dopaminergic neurons in the SN, it is increasingly recognized that nonmotor symptoms, including cognitive and memory impairments, play a significant role in the disease

Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation

Immunocomplexes were visualized via chemiluminescence using a Chemidoc MP Imaging System (Bio-Rad Laboratories, Hercules, CA, United States) and analyzed with the software ImageJ 1.7.0