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Interestingly, NEUROD2 was identified by the elegant transactivator trap genetic screen designed by the Ghosh team as an activity-dependent transcription factor, like CREB

[DOI] [PMC free article] [PubMed] [Google Scholar] 117.Evangelista AM, Thompson MD, Bolotina VM, Tong X, Cohen RA

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Intriguingly, many of these effects are mediated through the modulation of the Wnt/-catenin signaling pathway, positioning TCM as a promising avenue in the therapeutic landscape of breast cancer
