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Description
Fisetin-induced PTEN expression reverses cellular senescence by inhibiting the mTORC2-Akt Ser473 phosphorylation pathway in vascular smooth muscle cells

10.3389/fendo.2021.667422 204 LinB.LeiY.WangJ.ZhuL.WuY.ZhangH.et al (2021a)

Curr Pharm Design (2005) 11(19):252531

USA 111 , 62036208 (2014)

discovered that SIRT1 could be desumoylated at lysine 734 by senstrin-specific protease 1 (SENP1), and that elevated SIRT1 sumoylation increased its stability and deacetylase activity in vitro (79)

Phenomics Cham Switz
