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The effect of dietary supplements in fibromyalgia has recently been investigated in a few studies, but these had methodological limitations, such as small sample sizes and, in many cases, the concomitant use of other therapeutic strategies [28, 29, 31, 32, 89, 91]

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Duration of treatment also appeared to be a factor and will need to be carefully considered in the design of future clinical trials in non-ambulatory SMA subjects

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