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Other methods of controlling ICP include drainage of cerebrospinal fluid through a ventriculostomy (drainage tube placed into a brain ventricle) and deep sedation with chemical paralysis

For deeper hyperpigmentation (post-acne scars, melasma), plan for at least 812 weeks of consistent daily use

It appears that between the fourth and tenth month is when the clinical picture is most likely to appear, but there are also cases reported earlier, as well as in older children