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According to the mitochondrial hypothesis and the oxidative stress hypothesis, mitochondrial dysfunction and oxidative stress are involved in the pathogenesis of AD, which can be both the initiating and accompanying processes in the pathophysiology of AD and the development of neurodegenerative processes in AD

(B) Soft agar colony formation assay in AGS cells

But for melasma, which is one of the more stubborn forms of hyperpigmentation, an over-the-counter serum might not be strong enough to deliver results, he says

Secondary plots revealed a type- and charge-dependent decrease of the true k cat value for the E170X mutants

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Phototherapy, particularly PDT and PTT, has emerged as a promising alternative, especially when used in combination with conventional treatments, where it exhibits strong synergistic potential [85]