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Response to treatment with GH therapy is poorer in children with radiation induced GH deficiency than in children with congenital GHD

A natural PPAR-gamma agonist, 15-deoxy-delta 12,14-prostaglandin J2, may act as an enhancer of PAI-1 in human proximal renal tubular cells under hypoxic and inflammatory conditions

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An overview of the spectrum of adverse effects is in Box 14.1

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