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Description
Gut Microbiota-Derived Indole 3-Propionic Acid Protects Against Radiation Toxicity via Retaining Acyl-CoA-Binding Protein

The vehicle group received a phosphate buffered saline (PBS) solution without any active treatment

This property is used for feedback inhibition of DGCs and probably for the downstream signaling by PilZ receptors

Endocrinology 140 , 40154023 (1999)
doi:10.1136/gutjnl-2011-301708 27

During exercise, skeletal muscle produces BDNF and releases lactate into the bloodstream, which crosses the blood-brain barrier and triggers additional BDNF expression in the brain
