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doi: 10.1172/jci84491 66 YangSZengJHaoWSunRTuoYTanLet al

*Correspondence: Yun Sun, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

J Genet

Abbreviations UC: Ulcerative colitis Keap1: Kelch-like ECH-associated protein 1 Nrf2: Nuclear factor erythroid 2-related factor 2 GPX4: Glutathione peroxidase 4 NQO1: NAD(P)H quinone dehydrogenase 1 MUC2: Mucin 2 GSH: Glutathione ROS: Reactive oxygen species xCT: Cystine/glutamate antiporter FTH1: Ferritin heavy chain 1 MDA: Malondialdehyde References Buie, M

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While combination therapies might improve effects, they can also increase the overall price levels