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RIP3 levels were found to be elevated after APAP overdose in mice102,103, and RIP3 deficiency provided early protection against liver injury, though this was not sustained102

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Monospecific low molecular weight ligands are the type of ligands that bind to a single or a small number of proteins or target molecules

Zaw MT, Emran NA, Lin Z

Retrieved 25 February 2020

After necropsy, kidney tissue of the remaining animals was split and parts further processed for FACS L/D staining, snap-frozen in liquid nitrogen and placed in 4% PFA for diffusion fixation