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Free-radical chain reaction occurs in an oxidatively-compromised environment where ROS production overcomes their removal

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Platelet activation by Shiga toxin and circulatory factors as a pathogenetic mechanism in the hemolytic uremic syndrome

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L., Wang Y

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Such acetylation homeostasis is determined by the interplay between two classes of antagonistic enzymes, histone acetyltransferases (HATs) and histone deacetylases (HDACs), which transfer or remove, respectively, an acetyl moiety of a lysine residue mapping in the N-terminal tail of nucleosomal histones 7

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Optional research biomarkers: senescence markers (p16^INK4a, SA--gal), SASP cytokine profile (IL-6, IL-1, MMPs) if lab resources permit

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We arent the only ones who think so

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