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Activated KCs secrete pro-inflammatory cytokines such as tumor necrosis factor (TNF), IL-1, and IL-6, recruiting neutrophils and circulating monocytes through the CC-chemokine ligand 2 (CCL2)-CC-chemokine receptor 2 (CCR2) interaction

By using the Wizard mask to apply the highest heat you can tolerate (without hurting yourself) to your closed eyelids you loosen, or soften, the contents of your meibomian glands

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Strategies to help reduce this could include moving non-urgent decisions to an alternative time of the day and a silent cockpit rule to reduce non-urgent interruptions during ward rounds

ASC, an adaptor that bridges NLRP3 to caspase-1